antibacterial efficacy of the ah plus and ah26 mixed with amoxicillin, triple antibiotic pastes and nanosilver
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abstract
background and aim: bacterial elimination from root canal system is one of the aims in endodontic treatments, so the addition of antibiotics to sealers can increase their antimicrobial efficacy, as in this study we are determining the in-vitro antimicrobial effect of ah26 and ah plus sealers mixed with amoxicillin, triple antibiotic pastes and nanosilver on enterococcus faecalis. materials and methods: in this experiment, amoxicillin, triple antibiotic pastes and nanosilver powders were added at 10 % of total sealer weight to ah26 and ah plus sealers and then cultured freshly or after 1 , 3 , and 7 days setting with suspension of enterococcus faecalis for 24 hours. zones of growth inhibition for enterococcus faecalis were evaluated in each group. results: addition of nanosilver did not increase the antibacterial effect of sealers. combination of sealers with amoxicillin had the highest antibacterial efficacy in fresh condition. in the set specimens results demonstrated that the combination of sealer and triple antibiotic pastes had the greatest antibacterial efficacy. conclusion: amoxicillin and triple antibiotic pastes can significantly improve the antibacterial properties of ah plus and ah26 sealers. such properties usually decrease in time, but use of sealer-amoxicillin/-triple paste combination is still superior to using sealers alone or in combination with nanosilver.
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Journal title:
journal of dental research, dental clinics, dental prospectsجلد ۱۰، شماره ۴، صفحات ۲۲۰-۲۲۵
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